The first experimental introduction of a growth hormone (HGH) compound to a test subject occurred in 1956, with the source of the hormone derived from bovine origins. Historically, growth hormone (HGH) was derived from inanimate tissues. However, contemporary HGH is now produced synthetically. Research in GH and HGH is still ongoing, and the synthetically produced compounds are available only to research institutes and educational facilities. As a licensed professional, to procure growth hormone (HGH) for experimental study, click here to be redirected to Biotech Peptides.
Research suggests the most effective growth hormone (HGH) peptides available for online purchase are Growth Hormone Releasing Peptides (GHRP) and Growth Hormone Releasing Hormones (GHRH). Another potentially viable alternative could be a Growth Hormone Secretagogue, such as MK 677.
Organisms possess a physiological mechanism known as the somatotropic axis, responsible for the synthesis and secretion of growth hormone. The regulation of this process is governed by the growth hormone-releasing hormone (GHRH) and somatostatin (SRIF).
Findings imply the growth hormone (HGH) produced by the hypothalamic-pituitary axis may play a crucial role in maintaining overall health. Insufficient growth hormone levels can result in a compromised immune system, depressive activity, impaired muscle recovery, decreased bone density, and other implications [ii].
HGH peptides are comprised of amino acids covalently linked together through peptide bonds, thus giving rise to their designated name. Peptide introduction in test studies has been speculated to induce adipose tissue reduction, promote muscle cell hypertrophy, and enhance bone mineral density, but studies are still ongoing.
The action of HGH peptides?
Due to the wide variety of peptides, our primary focus will be on growth hormone (GH) secretion and surrounding research. The peptides under consideration encompass CJC, Ipamorelin, and other similar compounds.
Investigations purport that when presented to experimental test models, these peptides may induce the secretion of endogenous growth hormone. This may subsequently result in the following potential outcomes:
- Possible elevated lipase secretion resulting in adipocyte (adipose cell) weight reduction.
- Possible elevated secretion of glucagon resulting in mobilization of glycogen into skeletal muscle cells.
- Possible elevated secretion of insulin-like growth factor 1 (IGF-1) is considered to be a promoter of musculoskeletal development, dermal integrity, hair vitality, and multiple physiological processes.
CJC-1295 and Ipamorelin Peptide blend
Researchers speculate that this represents the optimal amalgamation for growth hormone secretion. CJC-1295 is classified as a Growth Hormone Releasing Hormone, whereas Ipamorelin falls under the Growth Hormone Releasing Peptides category.
Several studies have suggested that the concurrent presentation of growth hormone-releasing hormone (GHRH) and growth hormone-releasing peptide (GHRP) may lead to enhanced outcomes [i].
Due to the substantial augmentation of endogenous growth hormone secretion, researchers can anticipate outcomes akin to the presentation of pure HGH. Scientists hypothesize that the properties may encompass a reduction in weight and potential enhancement of muscular development.
Tesamorelin is a synthetic peptide hormone studied under conditions of excessive adipose tissue accumulation in the abdominal region. Specific conditions and behavioural patterns may possibly result in an increased accumulation of fatty tissue in the abdominal region, which may have adverse health implications. Research study findings suggest that Tesamorelin may potentially reduce adipose tissue within the study conditions.
Hexarelin is a growth hormone-releasing peptide (GHRP) frequently examined alongside growth hormone-releasing hormone (GHRH). Research suggests Hexarelin is a peptide compound that may potentially stimulate the secretion of growth hormone (GH), potentially leading to enhanced growth factor production.
Following research studies examining the potential impact of Hexarelin, researchers suggest the experimental test models begin experiencing adipose tissue reduction, the potential for lean muscle hypertrophy, and additional characteristics suggesting collagen synthesis.
Hexarelin is relatively less prevalent than CJC or Ipamorelin; however, numerous research studies have suggested its potential impact. The HGH-Fragment, or AOD 9604, is a peptide studied for its potential in elevating growth hormone (HGH) activity.
These compounds are classified as peptides and structurally similar to Growth Hormone. However, investigations suggest they may potentially induce a substantial decrease in adipose tissue mass. However, they have not been suggested to contribute significantly to muscle hypertrophy.
Researchers speculate both of these methods may potentially enhance body composition. The term “Fragment” or “Frag” refers to a specific segment of the Growth Hormone Amino Acid chain, specifically encompassing the final 15 amino acids (176-191).
AOD 9604, conversely, is a derivative of the aforementioned amino acids (176-191), allegedly conferring upon AOD the potential to regulate injuries through the augmentation of erythrocytes and the reduction of inflammatory responses.
MK 677 Peptide
MK 677 is frequently classified alongside Selective Androgen Receptor Modulators (SARMs), even though it does not possess the characteristics of an SARM. It is also not a peptide molecule. Standard Selective Androgen Receptor Modulators (SARMs) may exhibit affinity towards the Androgen Receptors located in both muscle and bone tissue, thereby inducing an upregulation in the synthesis of muscle protein.
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Scientists hypothesize that MK 677, on the other hand, may function as a growth hormone secretagogue, thereby abstaining from any interaction with the androgen receptors. Instead, it may solely induce an augmented Growth Hormone (HGH) secretion from the pituitary gland.
Elevated levels of growth hormone (HGH) have been associated with enhanced adipose tissue reduction and potentially augmented skeletal muscle accrual.
If you are a researcher interested in further studying any of the peptides mentioned in this article, visit Biotech Peptides. Remember that none of the compounds discussed here have been approved for human consumption and are strictly prohibited from personal use. Licensed professionals, academics, and scientists should only purchase and use these substances in confined laboratory environments.
[i] Veldhuis JD, Keenan DM, Bailey JN, Miles JM, Bowers CY. Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. Eur J Endocrinol. 2009 Aug;161(2):293-300. doi: 10.1530/EJE-09-0270. Epub 2009 May 20. PMID: 19458139; PMCID: PMC2772823.
[ii] 60 YEARS OF NEUROENDOCRINOLOGY: The hypothalamo-GH axis: the past 60 years in Journal of Endocrinology